AB Vector - Protein folding diseases targets

  Protein folding diseases targets
 
  AB Vector provides recombinant baculovirus stocks for the expression of several proteins which are misfolded and accumulate in protein folding diseases.

Tau is a neuronal microtubule-associated protein which is a key component of neurofibrillary tangles in Alzheimer's disease. Filamentous tau deposits in neurons or glial cells are also characteristic for Pick's disease, corticobasal degeneration and progressive supranuclear palsy (Hasegawa, Neuropathology, 2006, 26:484-90).

Alpha-synuclein is a major component of proteinaceous aggregates associated with Parkinson's disease and other synucleopathies, such as Lewy body dementia, Lewy body variant of Alzheimer's disease, and multiple system atrophy (Beyer, Acta Neuropathol, 2006, 112:237-51).

SOD1 (Cu, Zn-superoxide dismutase) misfolding is causative to amyotropic lateral sclerosis (Rakhit and Chakrabartty, Biochim Biophys Acta, 2006, 1762: 1025-37).
 
  Relevant products
 
Recombinant baculoviruses for expression of protein diseases targets
Cat # Product Specification Unit size Price*
PD3 BV-Tau352
Recombinant baculovirus stock
Expression of 352 aa Tau isophorm
1 ml, 108 p.f.u./ml $499.00
PD7 BV-Tau383
Recombinant baculovirus stock
Expression of 383 aa Tau isophorm
1 ml, 108 p.f.u./ml $499.00
PD9 BV-Tau381
Recombinant baculovirus stock
Expression of 381 aa Tau isophorm
1 ml, 108 p.f.u./ml $499.00
PD13 BV-Tau412
Recombinant baculovirus stock
Expression of 412 aa Tau isophorm
1 ml, 108 p.f.u./ml $499.00
PD14 BV-Tau412TR
Recombinant baculovirus stock
Expression of 412 aa Tau isophorm. T39-R mutant.
1 ml, 108 p.f.u./ml $499.00
PD15 BV-Tau412KE
Recombinant baculovirus stock
Expression of 412 aa Tau isophorm. K267-E mutant.
1 ml, 108 p.f.u./ml $499.00
PD17 BV-Synuclein
Recombinant baculovirus stock
Expression of alpha synuclein
1 ml, 108 p.f.u./ml $499.00
PD21 BV-Syn-GFP
Recombinant baculovirus stock
Expression of alpha synuclein-GFP fusion
1 ml, 108 p.f.u./ml $499.00
PD25 BV-SOD1
Recombinant baculovirus stock
Expression of SOD1
1 ml, 108 p.f.u./ml $499.00
PD29 BV-SOD1-GFP
Recombinant baculovirus stock
Expression of SOD1-GFP fusion
1 ml, 108 p.f.u./ml $499.00
 
  *Go to PRODUCTS to order online. Alternatively, email an order as pdf attachment to info@abvector.com, or send it by Fax to 1-760-454-2465 or call 1-866-683-2867 to order by phone.
 
  If you have not worked with recombinant baculoviruses, you can get a quick update at TECHNOLOGY. Go to BACULOVIRUS TUTORIAL for simple on-line instructions on baculovirus transfection, propagation of recombinant baculoviruses and recombinant baculovirus protein expression studies.
 
  Click on PRODUCTS to view the entire list of recombinant baculovirus-related products.


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