BV-Tau381™ is a recombinant baculovirus which provides for high level expression of human 381 a.a. tau isoform (Goedert et al., Neuron, 3: 519-526, 1989). The protein is expressed under control of a very strong p10 promoter. Sf9 cells infected with BV-Tau381™ form characteristic axon-like cell processes (Knops et al., J Cell Biol, 114: 725-733,1991).
If you have not worked with baculovirus expression system, also referred to as baculovirus expression vector system or BEVS, you can get a quick update at TECHNOLOGY. Go to BACULOVIRUS TUTORIAL for simple on-line instructions on baculovirus transfection, propagation of recombinant baculoviruses and recombinant baculovirus protein expression studies.
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